Piramal Pharma

Vaccines and Biologics

Piramal offers development and manufacturing services for large molecules through our associate company Yapan Bio. Based in Hyderabad, India, Yapan Bio has a proven track record in the successful development and manufacturing of various large molecules. Yapan specializes in process development, scale-up, and GMP-compliant manufacturing of vaccines and biologics, including high-containment product classes (up to BSL-2+), recombinant vaccines, viral vector-based vaccines, gene therapies, monoclonal antibodies, therapeutic proteins, and other complex biologics for Phase I/II human clinical trials.

Product Class:

Vaccines:

Recombinant vaccines
- Protein antigens
- Virus-like particles
- Nano-particles, etc.
Viral vector-based vaccines
RNA vaccines
DNA vaccines

Biologics/Bio-Therapeutics:

Gene therapy
- Oncolytic viruses
- Vectors (viral & non-viral), etc.
Monoclonal antibodies
Therapeutic proteins and other complex biologic

Services for Vaccines & Biologics

BROCHURE

Featured Services

Cell line development
Optimization and scale-up for high product titer, stability and consistent manufacturing output
Analytical method development and qualification
Formulation development
Stability studies

Establishment and qualification of small-scale model for different unit operations for the process
Classification of process parameters and product Quality attributes-critical, major, minor
Design of experiments (DoE) to establish the appropriate ranges for the process parameters and product quality attributes
Execution of experiments and generation of data/reports to support regulatory filings