Our facilities' extensive experience with Antibody Drug Conjugates (ADCs), bio-conjugates, and peptides positions us exceptionally well to serve our customers in these specialized categories. We excel in the complex processes required for the development and manufacturing of these advanced therapies, ensuring high efficacy and safety. Additionally, through our associate company Yapan Bio, we expanded our capabilities to include the development and manufacturing of vaccines and biologics, further enhancing our comprehensive service.
Piramal is a global leader in delivering customer centric solutions in the world of Antibody Drug Conjugates (ADCs) and Bioconjugates to global pharma and biopharma companies alike. Our world class facilities in UK and US, backed by a highly experienced team, offer integrated services, from conjugation to Clinical and Commercial ADC GMP Batch Manufacturing and Fill/ Finish.
Piramal offers development and manufacturing services for large molecules through our associate company Yapan Bio. Based in Hyderabad, India, Yapan Bio has a proven track record in the successful development and manufacturing of various large molecules. Yapan specializes in process development, scale-up, and GMP-compliant manufacturing of vaccines and biologics, including high-containment product classes (up to BSL-2+), recombinant vaccines, viral vector-based vaccines, gene therapies, monoclonal antibodies, therapeutic proteins, and other complex biologics for Phase I/II human clinical trials.
Piramal’s Turbhe facility specializes in the development and commercial manufacturing of peptides using both solution and solid-phase synthesis methods. Additionally, we provide a range of generic peptide APIs from multigram to kilogram scale. Our facility holds accreditations from USFDA, EDQM, AIFA, and KFDA.
Piramal’s Discovery Services (PDS) site in Ahmedabad, India, provides comprehensive discovery services including synthetic chemistry, in-vitro biology, in-vitro ADME, route scouting, and non-GMP scale-up to large/mid-size pharma, biotechs and academic institutions around the world. We commenced our operations in early 2003, focusing on aiding start-ups and biotech companies and have now grown to a team of over 300 scientists working in world-class chemistry laboratories. PDS can provide forward integration with the company’s drug substance and formulation sites in North America, UK and India.
The specialized team at Piramal Discovery Solutions (PDS) makes it one of the most reputed service providers for mg to kg scale discovery chemistry requirements and boasts of a broader experience in preparing high quality small molecule NCEs.
Piramal’s in vitro Biology is designed to provide best in class support to our clients to enable their preclinical drug discovery, including assay development, hit identification, hit-to-lead and lead optimization, including HTS, multiplex assay development, primary/secondary functional assays, HCS, and selectivity.
In vitro facilities at Piramal Discovery Services, Ahmedabad provide absorption, distribution, metabolism, and excretion (ADME) services for faster and improved decision making points or standalone offering to support drug discovery programs. Cost-efficient, standardized and customized assays for ADME parameters are provided to the clients.
Our fully equipped kilo lab provides rapid development of scalable and robust chemical processes using advanced process methodologies which is critical for quick supply in the early development phase and to understand the scalability of the original process.
The analytical team collaborates with the chemists and leads method development, preparative purification and characterization, allowing the chemists to focus on trouble-shooting which ensures better efficiencies and faster deliveries.
