Piramal Pharma Solutions, C-43, MIDC, T.T.C. Industrial Area, Next to Effort B.P.O, Opp Nocil RCD, Turbhe, off Thane- Belapur Road, Dist. Thane, Turbhe, Navi Mumbai- 400613, India
Piramal’s Turbhe facility offers strong expertise in the development and commercial manufacturing of both solution phase and solid phase synthesis of peptides. We also offer a portfolio of generic peptide APIs from multigram to kilogram scale. The facility is accredited by USFDA, EDQM, AIFA and KFDA.
The facility specializes in synthetic process development and optimization, including the evaluation of process intellectual property (IP) and the creation of non-infringing processes. It excels in isolating impurities from active pharmaceutical ingredients (APIs) and can develop and validate analysis methods for APIs and their intermediates. Additionally, it offers manufacturing services for fragments and intermediates.
The Turbhe facility excels in solid-phase and solution-phase peptide synthesis, downstream processing, and manufacturing long-chain peptide APIs. It also offers expertise in producing cost-effective building blocks, cleavages, deprotections, purification, impurity profiling, and freeze-drying services.
The facility specializes in synthetic process development and optimization, including the evaluation of process intellectual property (IP) and the creation of non-infringing processes. It excels in isolating impurities from active pharmaceutical ingredients (APIs) and can develop and validate analysis methods for APIs and their intermediates. Additionally, it offers manufacturing services for fragments and intermediates.
The Turbhe facility excels in solid-phase and solution-phase peptide synthesis, downstream processing, and manufacturing long-chain peptide APIs. It also offers expertise in producing cost-effective building blocks, cleavages, deprotections, purification, impurity profiling, and freeze-drying services.
The facility offers a range of capabilities for peptide synthesis and processing. It includes capability of handling milligram to multigram scales, five independent synthetic lines, and two downstream process lines equipped with axial compression columns for chromatography. Additionally, the facility features two dedicated freeze dryers for development purposes and a reverse osmosis facility.
The facility features a combined reactor volume of 4,500 liters, comprising 200-liter reaction vessels dedicated to solid-phase synthesis and tanks with capacities of up to 2,000 liters for synthetic modifications and downstream processing. With 14 production lines operating concurrently and 11 additional lines for downstream processing tasks such as HPLC purification, reverse osmosis, and filtration, it offers ample capacity for simultaneous and efficient production and processing.
We provide a comprehensive product portfolio encompassing nearly 90% of all generic peptide APIs, including both commercialized and under-development products. Additionally, we have successfully scaled up production for over 12 peptide APIs to meet commercial supply demands.
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Established track record in developing complex chemistries and scaling them up for commercial production.
Capability to integrate R&D of Peptide API development to its commercial manufacturing as well as formulation development and manufacturing through our global network of facilities.
Embracing a culture of quality, we integrate rigorous quality checks and balances throughout our operations, ensuring consistent and exceptional product quality. Our teams are dedicated to upholding the highest quality standards at all stages of the development process.
Peptide manufacturing began with Oxytocin.
Establishment of R&D center and new facility.
Batch manufacturing commenced at Turbhe.
Acquired by Piramal Pharma, with installation of higher capacity peptide purification columns (LC-45).
